AMPK connects energy stress to PIK3C3/VPS34 regulation
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چکیده
منابع مشابه
Metabolic Regulation of Neuronal Plasticity by the Energy Sensor AMPK
Long Term Potentiation (LTP) is a leading candidate mechanism for learning and memory and is also thought to play a role in the progression of seizures to intractable epilepsy. Maintenance of LTP requires RNA transcription, protein translation and signaling through the mammalian Target of Rapamycin (mTOR) pathway. In peripheral tissue, the energy sensor AMP-activated Protein Kinase (AMPK) negat...
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The AMP-activated protein kinase (AMPK) is an energy sensing enzyme that once activated, promotes energy production and limits energy utilisation to ensure cellular survival. In addition to targeting numerous metabolic enzymes for this purpose, it is becoming apparent that AMPK can also regulate a number of transcriptional processes. These processes ensure cell survival through the inhibition o...
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ژورنال
عنوان ژورنال: Autophagy
سال: 2013
ISSN: 1554-8627,1554-8635
DOI: 10.4161/auto.24877